Japanese researchers discovered that a chemical called sesaminol, abundant in sesame seed shells normally thrown out as waste, has protective effects against Parkinson’s disease. Feeding mice a diet containing sesaminol for 36 days saw an increase in dopamine levels and motor performance.

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TIL sesame seeds have shells. I mean like, obviously. Why the hell did I never consider that before?


Wonder if it would be effective helping those who have an essential tremor.


can we eat raw sesame seed to obtain the sesaminol or those it has to be processed by cooking it or something?


Is it still found in sesame seeds you buy at the market?


So, this study shows Sesaminol preventing cell death both in a test tube when we give a certain toxin to nerve cells, and in mice when we give a different toxin that works a similar way. It appears to do this through preventing oxidative stress. Oxidative stress is proposed as a major cause of Parkinson’s. *Maybe* sesaminol works in humans, and *maybe* it prevents other causes of oxidative stress, and *maybe* oxidative stress is the root cause of Parkinson’s but none of those things are certain. Worth a look, but lets be realistic here – there is a very good chance this will not work. One thing that is pretty certain is this has essentially no chance of working on anything where oxidative stress is not the root cause. So that means – no, this isn’t going to work for ADHD, schizophrenia, essential tremour, replace MAOI or any of the other things people are proposing. Sesaminol has no direct effect of dopamine, it only maybe has an indirect effect in Parkinson’s.