Adolescent cannabis use and later development of schizophrenia: An updated systematic review of six longitudinal studies finds “Both high- and low-frequency marijuana usage were associated with a significantly increased risk of schizophrenia.”

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This is very complex but our current vague understanding of schizophrenia shows us that the disorder is an example of gene-environment interaction. When the genetics are there, many environmental risk factors such as childhood trauma, drug abuse (like pot and hallucinogens), infectious agents (Toxoplasma gondii), and more wacky things we barely understand can express and trigger this genetic predisposition.

PaulieW8240

>Abstract. >Background. >The study aimed to review recent literature not included in previous reviews and ascertain the correlation between early marijuana use among adolescents, between 12 and 18 years of age, and the development of schizophrenia in early adulthood. A further aim was to determine if the frequency of use of marijuana demonstrated any significant effect on the risk of developing schizophrenia in early adulthood. Methods >Five hundred and ninety-one studies were examined; six longitudinal cohort studies were analyzed using a series of nonparametric tests and meta-analysis. Results >Nonparametric tests, Friedman tests, and Wilcoxon signed tests showed a highly statistically significant difference in odds ratios for schizophrenia between both high- and low-cannabis users and no-cannabis users. Conclusion >Both high- and low-frequency marijuana usage were associated with a significantly increased risk of schizophrenia. The frequency of use among high- and low-frequency users is similar in both, demonstrating statistically significant increased risk in developing schizophrenia. Most commenters on this post haven’t read the sub rules, let alone the abstract.

dude-O-rama

THC has been documented to increase the risk of psychosis, of which schizophrenia is one example. Marijuana has been bred in recent decades to have progressively higher levels of THC, and lower levels of CBD, which apparently would normally help to negate this effect. I was just watching the Kurzgesagt video on this this morning.

bjb406

With the massive surge in people using Marijuana over the world, it’s note worthy that cases of schizophrenia is relatively constant over the years, before and after introducing weed to countries.. But yeah, predisposed people can get worse by all changes in chemistry. Read a while ago, that work troubles and love troubles are the two leading causes of psychosis

RustySnail420

Smoking is bad for your health, no matter what you are smoking.

benjamarchi