Ketogenic Diets are safe and tolerable over a 6-month study period and yield improvements in body composition, fatigue, depression, QoL, neurological disability and adipose-related inflammation in persons living with relapsing MS.

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Interesting results, but unfortunately these types of studies are always riddled with biases that are difficult to account for. Specifically, enrolling patients into a single arm, unblinded (how could you blind this study? No idea. But it’s a problem regardless) study comparing people only against themselves really hurts the conclusions one can draw. The real issue is that people who are enrolling in this kind of study are likely motivated to be doing more about their overall health (eg diet and activity levels) than perhaps the overall population. As a result, one should not assume that the keto diet was the only factor at play here, since the chances are that participants were also likely engaging in other activities to promote better health (and mental health). This and the “tolerability” data could be particularly explained given such a short study duration. Hopefully access to the full study is available at some point, as there’s no report in the abstract about changes to medications, which can also influence the results, particularly in a single arm study, since it can’t be balanced by a control group. And it would also be good to know more about patient demographics at baseline.

jayhasbigvballs

Noooo I have genetic high cholesterol

Lysmerry

ketogenic turns on autophagy in the cells

Mcozy333

I thought that Keto diet increases inflammation and is not recommended especially for people with chronic pain (like in MS)

Skeith86

There’s a reason eating nothing but meat helps beat all my autoimmune conditions. It’s all linked to inflammation.

fresohoi